- Phone: 07946518372
- Email: info@edenmed.co.uk
- Mon-Fri: 8am-9pm
- Sat: 9am-5pm
Polynucleotide Skin Rejuvenation
Restore skin quality from within with Polynucleotide Skin Rejuvenation. This advanced regenerative treatment improves hydration, elasticity and overall skin health for a naturally smoother, firmer and more radiant complexion.
Quick Summary
Polynucleotide Skin Rejuvenation stimulates natural skin repair, boosts collagen and hydration, and improves texture, elasticity, and radiance for healthier, younger-looking skin with minimal downtime.
Minimal Downtime Visible Results For Face & Body
Polynucleotide Skin Boosters
Serving -Westminster and Greater London, Poole and Dorset
SkinBrytePBP
Click on image for the brightest skin possible
Polynucleotide - "Salmon Sperm Treatment" Advanced Skin Regeneration at EdenMed Clinic
Advanced Skin Regeneration at EdenMed Clinic
Excellent for smoother, firmer, more hydrated and naturally rejuvenated skin. Polynucleotides at EedenMed Clinic offer one of the most advanced regenerative treatments in modern aesthetic medicine.
Often called the “Salmon Sperm Treatment” in the media, polynucleotides (PN/PDRN) provide powerful, natural skin boosting without adding volume. This makes them ideal for clients wanting fresher, younger-looking skin while still looking like themselves.
At EdenMed Clinic, Dr Sam (injectable) and Annie (via microneedling) deliver medical-grade polynucleotides using the world’s most trusted brands, including NucleoFill, PhilArt, Plinest and Ameela.
What Are Polynucleotides?
Polynucleotides (PDRN) are purified DNA fragments derived from trout or salmon sperm. These activate the skin’s deep regenerative processes. They work on the biology of ageing—repairing, rebuilding and restoring compromised tissue.
How Polynucleotides Work
They trigger powerful cell-repair pathways by:
- Repairing damaged or ageing cells
- Stimulating fibroblasts for increased collagen and elastin
- Boosting deep hydration (hydro-balancing)
- Improving microcirculation and oxygenation
- Reducing inflammation and redness
- Strengthening thin, crepey or fragile skin
The result is firmer, brighter, clearer, stronger, and more resilient skin that improves naturally over weeks.
Why Choose Polynucleotide Treatment
Polynucleotides are the perfect treatment for clients who want natural rejuvenation without changing facial shape or adding volume.
They effectively treat:
- Fine lines
- Thin, crepey or fragile skin
- Under-eye hollowing and dark circles
- Acne scarring
- Large pores
- Redness & inflammation
- Neck laxity and lines
- Sun damage
- Dull or dehydrated skin
Many EdenMed clients choose this treatment to refresh tired eyes, restore hydration, firm the neck, and strengthen ageing skin.
Polynucleotide treatment areas at EdenMed
We treat almost every facial and body area, including:
- Under-eye area (dark circles, crepey skin)
- Cheeks & mid-face
- Neck and jawline
- Décolletage
- Hands
- Forehead & frown area
- Acne scarring
- Full-face bioregeneration
- Knees, elbows, and other areas of laxity
- Every treatment plan is bespoke to your skin’s unique needs.
Polynucleotides vs Dermal Fillers — What’s the Difference?
Polynucleotides
- Improve skin biology
- Boost collagen/elastin
- Reduce inflammation
- Strengthen and repair
- Natural, subtle results
Dermal Fillers
- Add volume & shape
- Replace lost structure
- Lift/contour areas
- Provide immediate change
- Sculpting and definition
Most clients combine both for global rejuvenation, but polynucleotides are ideal if you want subtle, natural regeneration.
Polynucleotide Brands We Use
We provide only clinically proven, medical-grade formulas:
Ameela (formerly NucleoFill Soft Eyes)
The world-leading treatment for delicate under-eye regeneration.
NucleoFill Medium / Strong
For full-face restructuring, firmness, and hydration.
PhilArt / Croma PolyPhil
My preferred choice—exceptional biocompatibility for sensitive or reactive skin.
Plinest
One of the most clinically researched PN formulations available.
Dr Sam will recommend the safest and most effective brand for your concerns.
Your Polynucleotide Treatment Journey
Consultation & Skin Assessment
A full medical consultation with Dr Sam or Annie to understand your concerns and goals.
Personalised Treatment Plan
Most clients need a course of 2–4 treatments, spaced 2–3 weeks apart.
Treatment Session
Performed using microcannulas where appropriate for reduced discomfort and increased safety.
Gradual, Natural Results
Improvements develop over 6–12 weeks, with ongoing regeneration following each session.
Maintenance
Every 6–9 months to maintain optimal skin quality and radiance.
Why Choose EdenMed
Doctor-led aesthetic clinic
Treatments performed or overseen by Dr Sam, GMC-registered and surgically trained.
Advanced anatomical expertise
Ensures safer, more precise polynucleotide placement.
Premium regenerative products
We use only the safest, medically researched global brands.
Natural-first philosophy
We enhance your features—never alter them.
Calm, discreet location
Personalised, high-standard medical care in the heart of the town.
Who Is This Treatment For?
Polynucleotides are suitable for:
- Men and women aged 25–70+
- Anyone wanting natural rejuvenation
- Clients with thinning, tired, or dehydrated skin
- Those unsuitable for fillers
- All skin types (Fitzpatrick I–VI)
- People wanting subtle, “undetectable” improvement
If you want quietly effective, scientifically proven skin repair, polynucleotides are ideal.
How Long Do Polynucleotide Results Last?
Most clients enjoy results for 6–12 months, influenced by:
- Skin condition
- Lifestyle
- Treatment area
- Brand used
Repeat maintenance ensures long-term radiance and tissue quality.
Book Your Polynucleotides Treatment
Healthier, firmer, naturally rejuvenated skin begins here.
Whether you want to brighten tired eyes, repair sun damage, strengthen ageing skin or simply refresh your appearance, polynucleotides at EdenMed Clinic offer one of the safest and most effective regenerative treatments available.
- Where science and natural beauty meet.
- Book your consultation today and begin your journey to naturally confident, radiant skin.
- Minimal dyscomfort, safe
- Natural collagen stimulation
- All treatments performed by an expert
- Dedicated aftercare and free follow-up
The treatment begins with a detailed discussion and analysis of your concerns and aspirations.
The results of polynucleotides are often immediate and improve with additional treatments.
We are devoted to combining a highly bespoke and personal approach, expert treatments, the highest standard of clinical care and dedicated follow up, from an experienced team and highly qualified, surgically trained doctor. We put our clients at the centre of all treatments and deliver a service comparable to no other clinic.